Super CitriMax® Demonstrates Long-Term Safety
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Super CitriMax®, an extract of Garcinia cambogia containing 60% (–)-hydroxycitric acid, has been previously shown to effectively aid weight management in human subjects. The historical use of this dried fruit rind as a condiment in Southeastern Asia, as well as the results of acute, short-term toxicity studies, indicate the safety of Super CitriMax. To assess its long-term safety, a variety of standard tests were conducted in Sprague-Dawley rats. The animals were fed Super CitriMax at varying concentrations of their food intake (0.2, 2.0 and 5.0%) over 1, 2 and 3 month periods. No histopathological (microscopic) changes were observed in vital organs. Neither fragmentation of DNA nor lipid peroxidation in liver and testis differed between Super CitriMax-fed animals and controls, showing that Super CitriMax does not damage genetic material or cellular lipids in these tissues. Taken together, these and previously reported results suggest that Super CitriMax is a safe and effective dietary supplement for weight control.
Source: Shara M, Ohia SE, Yasmin T, et al. Mol Cell Biochem. 2003;254:339-46.
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