Super CitriMax® Shown Clinically Effective in Weight Management

Super CitriMax®, a highly bioavailable form of (-)-hydroxycitric acid (HCA), has been shown to reduce appetite, inhibit fat production and decrease body weight. The current study evaluated the effects of Super CitriMax® alone and in combination with ChromeMate® niacin-bound chromium plus Gymnema sylvestre extract (patent-pending), as part of a weight loss program of supervised exercise and calorie restriction. Three groups of obese subjects were randomly assigned to receive 4,667 mg of Super CitriMax® (2,800 mg HCA) daily, or the Super CitriMax® combined with 400 mcg chromium plus 400 mg gymnema extract, or placebo. After 8 weeks, the Super CitriMax® group resulted in a 6.3% decrease in body weight and Body Mass Index (BMI, an indicator of healthy body weight). Levels of serum serotonin, a mechanism of appetite control and eating behavior, increased 40%, while food intake decreased by 4%. The Super CitriMax® group also showed 6.3%, 12.3% and 8.6% reductions in total cholesterol, LDL and triglyceride levels, respectively, while beneficial HDL cholesterol increased 10.7%. Excretion of urinary fat metabolites, and indicator of "fat burning," significantly increased, as well. The combination group resulted in even greater improvements in all parameters tested. In contrast, no significant changes in weight loss, BMI, food intake, blood lipids or fat metabolites were observed in the placebo group at the end of 8 weeks, while small increases in serotonin levels occurred. These results suggest that Super CitriMax® alone, and to a greater degree the combination of Super CitriMax® plus ChromeMate® and Gymnema, are safe and effective dietary ingredients for promoting weight control and healthy blood lipid levels.

Source: Preuss HG, Bagchi D, Bagchi M, Rao CVS, Satyanarayana S, Dey DK, Efficacy of a Novel, Natural Extract of (-)-Hydroxycitric Acid (HCA-SX) and a Combination of HCA-SX, Niacin Bound Chromium and Gymnema sylvestre Extract in Weight Management in Human Volunteers: A Pilot Study, Nutrition Research, 24:45-58, 2004.