Super CitriMax®, a novel calcium/potassium-bound hydroxycitric acid complex (HCA-SX) derived from Garcinia cambogia, has been reported to suppress body weight regain and food intake in laboratory animals following substantial weight loss. Conjugated linoleic acid (CLA) has been shown to reduce body fat by increasing fatty acid oxidation, or the burning of fat as fuel. The soluble fiber guar gum appears to blunt food intake by slowing the digestive process and increasing satiety, the feeling of fullness. The current study examined whether CLA and guar gum modify the long term effects of HCA-SX on weight regain. Rats were fed calorie-restricted diets for 10 days, then divided into 7 groups and allowed to consume food freely. Animals fed HCA-SX at 3% of the diet consumed significantly less food and regained less body weight compared to controls, as did all groups fed HCA-SX (HCA-SX with guar gum or guar gum and CLA along with HCA-SX). However, neither CLA (1%) nor guar gum (3%) combined with HCA-SX increased the effectiveness of HCA-SX alone on blunting food intake and weight regain. When given separately, CLA and guar gum had no effect on these parameters. The combination of HCA-SX and CLA, as well as HCA-SX combined with CLA and guar, led to a lower fat content in the liver. These results demonstrate that HCA-SX is effective at blunting food intake and weight regain after significant loss of body weight, while CLA and guar gum do not further enhance these effects. The present study supports the use of Super CitriMax® as a safe, effective weight management aid for appetite suppression, weight loss and weight maintenance.

Source: Leonhardt M, Munch S, Westerterp-Plantenga M, Langhans W, Effects of Hydroxycitrate, Conjugated Linoleic Acid, and Guar Gum on Food Intake, Body Weight Regain, and Metabolism After Body Weight Loss in Male Rats, Nutrition Research, 24:659-669, 2004.