The principal phytoestrogen in Protykin® binds with estrogen receptors and produces estrogen-like effects in women. These effects may be helpful during menopause by reducing hot flashes, depression and osteoporosis (bone loss), in addition to the known cardiovascular benefits.

Source: Calabrese G, Nonalcoholic Compounds of Wine: The Phytoestrogen Resveratrol and Moderate Red Wine Consumption During Menopause, Drugs under experimental and clinical Research, XXV:111-114, 1999.