Researchers at the University of Connecticut School of Medicine, Harvard Medical School and Creighton University found that Protykin®, a 200:1 standardized extract of Polygonum cuspidatum (root), was protective against experimentally-induced heart tissue damage. Heart tissue of animals treated with Protykin® for three weeks prior to injury showed improved ventricular function and blood flow as well as reduced tissue damage and oxidative stress. The cardioprotective effects of Protykin appear to be related to its potent free radical scavenging ability.

Source: Sato M, Maulik G, Bagchi D, Das DK, Myocardial Protection by Protykin, A Novel Extract of trans-Resveratrol and Emodin, Free Radical Research, 32:135-144, 2000.

Researchers at Creighton University and the University of Connecticut found that Protykin®, a 200:1 standardized extract of Polygonum cuspidatum (root), was cardioprotective in experimental animals. Measures of heart function were improved following three weeks of treatment. Protykin® significantly inhibited the formation of oxygen free radicals, reduced other measures of oxidative stress, and improved recovery of heart function following experimentally-induced cardiac stress.

Source: Bagchi M, Das DK, Bagchi D, Protykin: A Novel Antioxidant, Cardioprotectant and Natural Phytoestrogen, The Meeting of the Society for Free Radical Research Europe. Free Radicals and Antioxidants in Nutrition: A Complex Matter of Balance, Roma, Italy, Pg 30, June 22-24, 2001.